TABLE 5.
VRP immunogenicity in macaques on day 56 postvaccination
| VRP type | Mean PRNT80 (no. of animals responding/no. of animals tested)a |
|||||
|---|---|---|---|---|---|---|
| VEEV-IAB | VEEV-IC | VEEV-ID | VEEV-IE | WEEV | EEEV | |
| VEEV | 3,200 (6/6) | 667 (6/6) | 43 (6/6) | 307 (6/6) | <20 (0/6) | <20 (0/6) |
| WEEV | ND | ND | ND | ND | 80 (4/6) | ND |
| EEEV | 160 (1/6) | 50 (1/6) | <20 (0/6) | 20 (1/6) | <20 (0/6) | 163 (6/6) |
| V/W/E | 5,647 (12/12) | 142 (9/12) | 87 (3/12) | 57 (6/12) | 53 (9/18) | 417 (12/12) |
| Mock | <20 | <20 | <20 | <20 | <20 | <20 |
Values are reciprocals of the endpoint dilution. ND, not determined.