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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Pain. 2014 May 9;15(8):815–826.e1. doi: 10.1016/j.jpain.2014.04.007

Figure 5. IC-CC connectivity is associated with decreased experimental pain thresholds in FM patients.

Figure 5

Figure 5 displays connectivity in FM patients between the IC and mid CC and IC. Connectivity between the L mid IC seed and the L MCC was negatively associated with “slightly intense” pressure thresholds (top). Also, connectivity between the L mid IC seed and the R MCC was negatively associated with “faint” pressure thresholds (middle). Finally, connectivity between the R posterior IC seed and the left mid IC was negatively correlated with “faint” pressure thresholds (bottom). In all cases, this result shows that FM patients display decreased experimental pain thresholds as IC-CC and IC-IC connectivity increases. CC = cingulate cortex, FM = fibromyalgia, IC = insula cortex, L = left, R = right.