Skip to main content
. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: J Neurochem. 2013 Jul 22;126(5):591–603. doi: 10.1111/jnc.12345

Table 1.

Mean (± SEM) putamen tissue concentrations and ratios of catechols in control subjects and patients with Parkinson’s disease

Control (14) PD (17)
Age (years) 74 ± 2 77 ± 1
Gender (% male) 86% 77%
PMI (hours) 12.1 ± 1.5 8.9 ± 1.5
DOPA 1.76 ± 0.59 0.61 ± 0.12*
DA 15.5 ± 2.09 1.00 ± 0.36****
DOPAL 0.496 ± 0.164 0.071 ± 0.036****
DOPAC 3.48 ± 0.66 0.164 ± 0.057****
DOPET 0.042 ± 0.013 0.007 ± 0.003***
NE 0.220 ± 0.034 0.054 ± 0.021****
DHPG 0.019 ± 0.003 0.004 ± 0.001****
DOPAL : DA 0.030 ± 0.006 0.144 ± 0.044**
DA : DOPA 16.5 ± 2.86 1.90 ± 0.68****
DOPAC : DOPAL 11.3 ± 2.50 3.39 ± 0.60**
DOPAC : DA 0.29 ± 0.08 0.31 ± 0.10
DOPET : DOPAC 0.012 ± 0.002 0.122 ± 0.062*
NE : DHPG 15.4 ± 3.45 10.8 ± 3.45

Different from control,

*

p < 0.05;

**

p < 0.001;

***

p < 0.001;

****

p < 0.0001.

Tissue concentrations are in pmol/mg wet weight.

Numbers of subjects are in parentheses.