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. 2014 Jun 16;111(26):9585–9590. doi: 10.1073/pnas.1402485111

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Fig. 2. — MOZ regulates proliferation and zonal formation within the GC. (A–D) GC B cells were assessed for DZ and LZ proportions using CD86 and CXCR4 to differentiate these zones by flow cytometry. (A) NP⁺Fas^hiIgD^lo B cells were assessed for zonal formation at day 7 postimmunization in Mb-1^Cre/+ and Moz^fl/flMb-1^Cre/+. (B–D) Ratio of DZ to LZ GC B cells (B) and number of DZ (C) and LZ (D) GC B cells. Mb-1^Cre/+, black bars; Moz^fl/flMb-1^Cre/+, white bars. Data are combined from three (day 7) and two (day 13) experiments; n = 5–10 per genotype. Error bars indicate ± SEM. *P < 0.05, **P < 0.01, ****P < 0.0001. (E and F) Cell-cycle analysis of day 7 sort-purified GC B cells from Mb-1^Cre/+ (black bars) and Moz^fl/flMb-1^Cre/+ (white bars). Data are combined from two experiments; n = 6 per genotype. Error bars indicate ± SEM. *P < 0.05, **P < 0.01.