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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Anticancer Res. 2013 Dec;33(12):5261–5271.

Figure 4.

Figure 4

Histopathological and immunohistochemical analysis of dextran sulfate sodium (DSS)-induced colitis. A: Colonic mucosa showing focal mucosal erosion and intense lymphoplasmocytosis in wild-type (WT) mice; B: Much less intense lymphoplasmocytosis within the lamina propria of the colonic mucosa in sEH−/− mice; C: Histogram of semi-quantification of active colitis (the percentage of inflamed area in the colon) showing a significant decrease of active colitis in sEH−/− mice compared to WT mice (p<0.05). Myeloperoxidase (MPO)-labeled neutrophils in active colitis in WT mice (D) and sEH−/− mice (E). F: Histogram of percentage of MPO-labeled neutrophils out of total cells counted showing a significant decrease of MPO-labeled neutrophils in sEH−/− mice compared to WT mice (p<0.05).