Fig. 1.
Within each functional network of interest, the average fractional anisotropy (FA) between constituent region-pairs was estimated to provide connection and network-level indices of structural connectivity for each subject. Depicted here are examples of white-matter tractography between 5 region-pairs (relevant to Network 1) in healthy controls and patients with schizophrenia. Visual inspection of tractography outputs was important to exclude problems in fibre tracking. However, our analysis focused on network-level differences and do not allow to declare changes at the level of single connections. Results from confirmatory analyses at the resolution of single connections can be found in Supplementary Fig. 2 (a = #20, b = #19, c = #1, d = #6, e = #22).