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. 2014 May 28;5:3912. doi: 10.1038/ncomms4912

Figure 4. Flexible fitting of the epithelial fusion failure 1 (EFF-1) crystal structure.

Figure 4

(a) Orthogonal views of the flexible fit of the EFF-1 domains and a lipid bilayer model into the electron cryo microscopic reconstruction. The resulting pseudo-atomic model is shown in ribbon representation and coloured according to the domain boundaries (domain I, red; domain II, yellow, domain III, blue; asterisk, unassigned density). (b) Schematic representation of the EFF-1 ectodomain. The domain assignment is based on the crystal structure23 (D1, domain I; D2, domain II; D3, domain III; MPR, membrane proximal region). See also Supplementary Movie 2.