Table 1.
Baseline patient characteristics, N = 340, WBRT – whole brain radiotherapy
| Characteristic | Patients |
|---|---|
| Median follow-up |
721 days |
| Sex |
|
| • Male |
159 (46.8%) |
| • Female |
181 (53.2%) |
| Median age |
62 |
| Age |
|
| • < 65 y |
208 (61.2%) |
| • ≥ 65 y |
132 (38.8%) |
| WBRT |
|
| • No |
189 (55.6%) |
| • Yes |
151 (44.4%) |
| RPA class |
|
| • I |
26 (7.7%) |
| • II |
271 (79.7%) |
| • III |
43 (12.6%) |
| Karnofsky Performance Score |
|
| • ≤ 70 |
82 (24.1%) |
| • > 70 |
258 (75.9%) |
| Number of cerebral metastases |
|
| • 1 |
197 (57.9%) |
| • 2 |
101 (29.7%) |
| • 3 |
31 (9.1%) |
| • 4 |
8 (2.4%) |
| • 5 |
2 (0.6%) |
| • 7 |
1 (0.3%) |
| Histology |
|
| • NSCLC |
160 (47.1%) |
| • SCLC |
27 (7.9%) |
| • Malignant Melanoma |
49 (14.4%) |
| • Breast Cancer |
41 (12.1%) |
| • Renal Cell Carcinoma |
20 (5.9%) |
| • Others |
43 (12.6%) |
| Median radiation volume |
1.7 ml |
| Median dose to the 80% isodose |
20 Gy |
| Radiation necrosis |
|
| • Yes |
21 (6.2%) |
| • No | 319 (93.8%) |