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Dissociation half-lives for yeast surface-displayed scFvs bound to DOTA complexes
| scFv | Hapten | Metal | Dissociation half-life* |
|---|---|---|---|
| 2D12.5ds | DOTA-Bn-Biotin | Y | 5.5 ± 1.3 |
| C8.2.5 | DOTA-Bn-Biotin | Y | 302 ± 13 |
| DOTA-Bn | Y | 53.1 ± 2.3 | |
| DOTA | Y | 3.5 ± 0.7 | |
| Lu | 3.8 ± 0.4 | ||
|
|
Calculated as ln(2)/koff and given in minutes as mean ± SD for n=3 experiments.
