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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Ann Surg. 2014 Apr;259(4):735–743. doi: 10.1097/SLA.0b013e3182a6909d

Table 2.

Uni- and multi-variate analyses for predicting lymph node metastasis in CRC patients

Univariate Multivariate
Variables HR$ 95%CI p value HR$ 95%CI p value
Pathological T stage (T3/4 vs. 1/2) 6.46 2.61–15.96 0.0024 2.38 0.81–7.03 0.11
Pathology (poor vs. mod/well differentiated) 2 0.57–6.98 0.2715 1.39 0.38–5.07 0.62
Venous Invasion (positive vs. negative) 4.59 2.13–9.89 0.0001 1.24 0.52–2.96 0.62
Lymphatic Invasion (positive vs. negative) 18.26 5.43–61.38 <0.0001 6.56 1.55–27.8 0.010
CEA (≥ 5 vs. <5) 6.25 2.45–15.92 0.0001 2.44 1.02–5.84 0.044
miR-200c in serum (high vs. low) 3.61 1.85–7.09 0.0001 4.81 1.98–11.7 0.0005

HR, Hazard Ratio; CI, Confidence Interval; CEA, Carcinoembryonic antigen; mod, moderately; TNM, tumor-node-metastasis staging

$

HR, hazard ratio for presence of lymph node metastasis in CRC patients