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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Ann Surg. 2014 Apr;259(4):735–743. doi: 10.1097/SLA.0b013e3182a6909d

Table 1.

Association between miR-200c expression in serum and primary CRC and various clinicopathological characteristics

Serum miR-200c (n =182) Tissue miR-200c (n=156)
Factors high
(n = 91)		 low
(n = 91)		 p value high
(n = 78)		 low
(n = 78)		 p value
Age ≦68 43 43 0.88 31 43 0.078
> 68 48 48 47 35
Gender Male 49 56 0.36 41 48 0.29
Female 42 35 37 30
Histological grade well/mod 83 82 0.99 69 71 0.79
poor/ mucinous 8 9 9 7
Tumor size ≦40(small) 47 42 0.50 38 40 0.87
> 40(large) 44 49 40 38
Serosal invasion Absent 26 29 0.78 27 18 0.12
Present 65 62 51 60
Lymph node met. Absent 43 64 0.0026 49 38 0.10
Present 48 27 29 40
Venous invasion Absent 52 53 0.99 49 38 0.10
Present 39 38 29 40
Lymphatic invasion Absent 20 26 0.39 26 10 0.0044
Present 71 65 52 68
Liver metastasis Absent 70 86 0.0015 71 67 0.45
Present 21 5 7 11
Peritoneal metastasis Absent 83 88 0.21 76 70 0.10
Present 8 3 2 8
Distant metastasis Absent 62 80 0.0023 68 59 0.099
Present 29 11 10 19

well, well differentiated; mod, moderately differentiated; poor, poorly differentiated