Table 4.
Concluded and ongoing trials on efficacy of tocilizumab in diseases other than rheumatoid arthritis (RA).
| Targeted diseases | Trial identifier |
|---|---|
| ClinicalTrials.gov (United States) | |
| Adult-onset Still's disease | NCT01002781 |
| Relapsing polychondritis | NCT01041248 |
| Type II diabetes, obesity | NCT01073826 |
| Grave's ophthalmopathy | NCT01297699 |
| Cardiovascular disease in RA | NCT01331837 |
| Polymialgia rheumatica | NCT01396317 |
| Giant cell arteritis | NCT01450137 |
| NCT01910038 | |
| Acute graft versus host disease | NCT01475162 |
| Non-ST elevation myocardial infarction | NCT01491074 |
| Systemic sclerosis | NCT01532869 |
| Transplant rates in highly sensitized patients awaiting kidney transplantation | NCT01594424 |
| Schizophrenia | NCT01696929 |
| Non-infectious posterior, intermediate or panuveitis | NCT01717170 |
| Castleman's disease | NCT01441063 |
| Juvenile idiopathic arthritis | NCT01734382 |
| Ovarian cancer | NCT01637532 |
| Fibrous dysplasia of bone | NCT01791842 |
| Primary Sjögren's syndrome | NCT01782235 |
| European Union Clinical Trials Registry | |
| Ankylosing spondylitis | 2009-017488-40, 2009-017443-34 |
| Cardiovascular disease in RA | 2010-020065-24 |
| Grave's ophthalmopathy | 2010-023841-31 |
| Systemic sclerosis | 2011-001460-22 |
| Erdheim Chester disease | 2012-003151-11 |
| Polyarticular-course juvenile idiopathic arthritis | 2011-001097-25 |
| Giant cell arteritis | 2011-006022-25 |
| UMIN-CTR clinical trial (Japan) | |
| ANCA-associated vasculitis | UMIN00002892 |
| Systemic sclerosis | UMIN00005550 |
| Neuromyelitis optica | UMIN00005889 |
| Chronic glomerulonephritis | UMIN00006080 |
| Colorectal cancer | UMIN00007493 |
| Takayasu arteritis | UMIN00007845 |
ANCA = anti-neutrophil cytoplasmic antibodies; UMIN-CTR = University Hospital Medical Information Network Clinical Trials Registry.