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. 2012 Mar 19;33(4):503–512. doi: 10.1038/aps.2011.193

Figure 1.

Figure 1

Blocking TLR2 and activating TLR9 markedly suppresses pulmonary metastasis of B16-F10 melanoma cells. (A) Representative lung samples. (B) The metastatic nodules were counted and data presented as the mean±SEM. n=15. (C) The pulmonary weight index of mice in the indicated treatment groups. Data are presented as mean±SEM. n=15 mice per group. (D) Kaplan-Meier graph representing the cumulative survival of mice in the indicated treatment groups. The data were analyzed using Kaplan-Meier survival analysis (n=15 per group). cP<0.01 vs sham. eP<0.05, fP<0.01 vs PBS. iP<0.01 vs anti-TLR2 plus CpG.