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. Author manuscript; available in PMC: 2014 Apr 28.
Published in final edited form as: Nat Cell Biol. 2009 Jul 20;11(8):934–942. doi: 10.1038/ncb1904

Figure 4.

Figure 4

ZIM/HIM-8 recruiting arrays associate with nuclear envelope components. (a-c) Combined FISH detection of extrachromosomal arrays (red) and immunolocalization of HIM-8 or ZIM-3 (yellow) and ZYG-12:GFP (green). HIM-8 (a) and ZIM-3 (b) recruiting arrays interact with a large patch of ZYG-12 at the nuclear envelope. The array shown in (c) does not recruit HIM-8 or any of the ZIM proteins, and does not colocalize with ZYG-12. Arrows indicate clear examples of co-localization (or lack thereof, in c). All images are maximum-intensity projections of deconvolved 3D stacks. Scale bars represent 5 μm.