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. Author manuscript; available in PMC: 2014 Dec 5.
Published in final edited form as: Cell. 2013 Dec 5;155(6):1216–1219. doi: 10.1016/j.cell.2013.11.019

Figure 1. Role of Autophagy in Tumor Progression and Fate.

Figure 1

(A) Autophagy promotes mammary tumorigenesis induced by PALB2 loss.

(B) Autophagy promotes the growth of KRASG12D-driven NSCLC. Lipid droplets are indicated in red, oncocytes are indicated in pink, and defective mitochondria are indicated in yellow.

(C) Autophagy promotes BRAFV600E-induced lung tumor growth.