Figure 2.
Overexpression of Tsr without sufficient CheA and CheW results in zippers. (A) A side view of a receptor zipper reveals two layers of membrane-bound receptors interacting at their membrane-distal tips. PD denotes periplasmic domains and IM inner membrane leaflets. The scale bar is 50 nm. Arrows indicate relative positions of subvolume averages shown at the right in panels B–D. Scale bars are 10 nm. (E–H) Model of receptor density from the subvolume average and manually fitted Tsr crystal structure from ref (46) in top view (E–G, levels roughly corresponding to B–D, respectively) and side view (H), showing the arrangement of receptors. Blue and yellow colors indicate receptors of opposing orientation.