Fig. 4.
A standard Radiation Therapy Oncology Group 0848 clinical target volume (orange) and planning target volume (red) are shown simultaneously with the proposed PTV80-final (blue) and PTV90-final (green) of this study on an anterior-posterior digitally reconstructed radiograph (A) and on axial (B), sagittal (C), and coronal (D) computed tomographic sections of 1 simulated patient as an example of where areas could potentially be reduced to minimize the toxicity of adjuvant treatment. PTV80-final = planning target volume containing 80% of mapped recurrences with avoidance of proximal organs at risk; PTV90-final = planning target volume containing 90% of mapped recurrences with avoidance of proximal organs at risk.