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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: J Immunol. 2014 Jan 31;192(5):2156–2166. doi: 10.4049/jimmunol.1300675

Figure 1. Type I IFNs promote Bcl6 expression.

Figure 1

(A, C, D) Bcl6 and T-bet staining in CD4+ T cells cultured in the presence of the indicated cytokines for 5 days. (B) Relative mRNA expression of Bcl6, T-bet, Maf, Irf-4, and Batf was evaluated by qPCR. The data (mean ± SD) are representative of three independent experiments. (E, F) Bcl6 and T-bet staining in CD4+ T cells cultured with increasing doses of IFN-α or IFN-β for 5 days (E) or in neutral conditions or IFN-β for the indicated number of days (F). Data (mean ± SD) are from duplicate cultures of three independent experiments (n=6). The plots are representative of three independent experiments. *, p<0.05; **, p<0.01.