Table 4.
General population cohorts. Pooled adjusted hazard ratios (95% confidence intervals) for end-stage renal disease subdivided for age groups <65 and >65 years. Shaded areas make up the combined reference groups.
| albumin-to-creatinine ratio (mg/g) or dipstick (classes)
|
||||||
|---|---|---|---|---|---|---|
| <10 Negative | 10–29 trace | 30–299 1+ |
≥300 ≥2+ |
All | ||
|
ESRD, younger than 65 years
| ||||||
| eGFR mL/min/1.73m2 | >105 | 12.4 (2.30–66.8) | 28.6 (6.45–127) | |||
| 90–104 | Ref | 14.2 (3.31–61.0) | 13.8 (1.87–101.2) | Ref | ||
| 75–89 | 5.81 (1.40–24.2) | 65.2 (37.3–114) | ||||
| 60–74 | 5.58 (2.00–15.7) | 87.3 (32.3–236) | ||||
| 45–59 | 3.1 (1.1–8.3) | 31.8 (14.3–70.5) | 55.4 (29.6–103) | 261 (112–610) | 9.5 (5.6–15.9) | |
| 30–44 | 101 (54.8–187) | 293 (69.3–1236) | 272 (107–693) | 828 (443–1545) | 110 (49.6–245) | |
| 15–29 | 999 (493–2023) | 3897 (1717–8845) | 2398 (1247–4609) | 5081 (2736–9435) | 1281 (556–2952) | |
|
| ||||||
| All | Ref | 13.7 (8.8–21.3) | 124 (60.2–257) | |||
|
| ||||||
|
ESRD, older than 65 years
| ||||||
| eGFR mL/min/1.73m2 | >105 | 0.0 (0.0–.) | 0.0 (0.0–.) | |||
| 90–104 | Ref | 0.0 (0.0–.) | 0.0 (0.0–.) | Ref | ||
| 75–89 | 0.0 (0.0–.) | 0.0 (0.0–.) | ||||
| 60–74 | 6.61 (1.61–27.2) | 18.8 (5.29–67.1) | ||||
| 45–59 | 3.4 (1.6–7.2) | 9.6 (3.8–24.4) | 16.4 (5.85–45.9) | 41.4 (7.95–215) | 4.5 (3.0–6.75) | |
| 30–44 | 11.5 (5.97–22.1) | 18.1 (3.83–85.9) | 90.8 (48.3–171) | 268 (157–458) | 42.1 (28.7–61.7) | |
| 15–29 | 131 (62.7–274) | 115 (33.8–389) | 413 (222–768) | 1071 (645–1779) | 186 (92.9–372) | |
|
| ||||||
| All | Ref | 10.3 (5.96–17.8) | 47.5 (27.2–82.9) | |||
Abbreviations are: eGFR. estimated glomerular filtration rate.