Table 2A.

All loss cues vs. neutral cue: Peak voxels for regions commonly activated in previous studies of the Monetary Incentive Delay (MID) task. Peak voxels within anatomic masks of each region are reported for the contrast all loss cues vs. the neutral cue. Reported peak voxels for thalamus and insula are restricted to anatomic subdivisions of interest–anteromedial thalamus and anterior insula, respectively–that were used for DCM. Small-volume corrected p<0.05, family-wise error (FWE). MNI coordinates.

	Adults			Adolescents
	p-value	T-score	x,y,z	p-value	T-score	x,y,z
Nucleus accumbens (r)	< 0.001	5.25	12,14, −2	0.012	3.61	10,10, −6
Nucleus accumbens (l)	0.004	4.01	−12,12, −6	0.008	3.85	−6,16,0
Insula (r)	0.002	5.33	32, 26, −6
Insula (l)
Thalamus (r)	0.018	3.55	8, −12,6	0.019	3.61	2, 0, 10
Thalamus (l)	0.023	3.45	− 8, 0, 4	0.042	3.21	−6, 0, 10
Putamen (r)	<0.001	7.51	26, 2, 2
Putamen (l)	0.002	4.76	−16, 6,0
Caudate (r)	<0.001	5.38	12,12,0
Caudate (l)	0.020	3.75	−10,12,0	0.022	3.79	−4, 8, 14
Amygdala (r)	0.027	3.32	28, − 4, −10
Amygdala (l)	0.037	3.13	−18, 2, −12	0.008	3.85	−6,16,0
Anterior cingulate cortex (r)	0.013	4.36	4, − 2, 48
Anterior cingulate cortex (l)	0.003	5.03	− 4, 4, 44
Motor cortex (r)	0.001	5.77	2 44, − 6, 50
Motor cortex (l)	<0.001	6.03	−36, −12, 58	0.025	4.47	−42, −16,54
Premotor cortex (r)	<0.001	6.04	2, − 2, 56
Premotor cortex (l)	<0.001	6.07	− 4, − 4, 56