Table 2.
Objective response rate according to patient characteristics
| n/N | Proportion with objective response (95% CI)* | |
|---|---|---|
| Age | ||
|
| ||
| <65 years | 74/123 | 60·2% (50·9–68·9) |
| ≥65 years | 13/20 | 65·0% (40·8–84·6) |
|
| ||
| Sex | ||
|
| ||
| Men | 46/71 | 64·8% (52·5–75·8) |
| Women | 41/72 | 56·9% (44·7–68·6) |
|
| ||
| ECOG PS score | ||
|
| ||
| 0 | 29/53 | 54·7% (40·4–68·4) |
| 1 | 46/72 | 63·9% (51·7–74·9) |
| 2 | 12/17 | 66·7% (44·0–89·7) |
| 3 | 0/1 | 0·0% (0·0–97·5) |
|
| ||
| Number of previous advanced or metastatic systemic treatments | ||
|
| ||
| 0 | 14/22 | 63·6% (40·7–82·8) |
| 1 | 26/44 | 59·1% (43·2–73·7) |
| 2 | 20/31 | 64·5% (45·4–80·8) |
| ≥3 | 27/46 | 58·7% (43·2–73·0) |
|
| ||
| Ethnic origin | ||
|
| ||
| Asian | 30/39 | 76·9% (60·7–88·9) |
| Non-Asian | 57/104 | 54·8% (44·7–64·6) |
143 patients were evaluable for response. ECOG PS=Eastern Cooperative Oncology Group performance status.
*
Using the exact method based on the F distribution.