Table 1.
Top 30 genes up-regulated by Poly I:C in fibroblasts.
| Symbol | Description | Fold change |
|---|---|---|
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 129 |
| CCL5 | chemokine (C-C motif) ligand 5 | 118 |
| CCL5 | chemokine (C-C motif) ligand 5 | 115 |
| OASL | 2'–5'-oligoadenylate synthetase-like | 83.3 |
| CCL8 | chemokine (C-C motif) ligand 8 | 78.5 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 76.3 |
| IFI27 | interferon, alpha-inducible protein 27 | 70.6 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 57.2 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 54.1 |
| GBP4 | guanylate binding protein 4 | 48.1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
45.6 |
| BST2 | bone marrow stromal cell antigen 2 | 43.4 |
| IL18BP | interleukin 18 binding protein | 43.4 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 43.1 |
| CFB | complement factor B | 41.4 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
41.2 |
| OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 40.9 |
| HERC5 | hect domain and RLD 5 | 38.8 |
| OAS2 | 2'–5'-oligoadenylate synthetase 2, 69/71kDa | 37.7 |
| OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 36.9 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
36 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 35.6 |
| OASL | 2'–5'-oligoadenylate synthetase-like | 33.8 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 30.6 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 30.5 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 29.6 |
| CD38 | CD38 molecule | 28 |
| IFI6 | interferon, alpha-inducible protein 6 | 27 |
| MX2 | myxovirus (influenza virus) resistance 2 (mouse) | 25.1 |
| IL6 | interleukin 6 (interferon, beta 2) | 24.5 |
Genes regulated by Poly I:C were filtered (p<0.05, FDR<0.05). Values in third column indicate -fold change ranked from highest to lowest