Figure 6. Anti-OX40 infusion increases tumor-specific immune response.
(A-B) PBMC from two patients with melanoma, before and after anti-OX40, were co-cultured with either autologous, HLA-mis-matched melanoma cell lines or flu. IFN-γ in the supernatant was measured by ELISA. Anti-tumor-specific antibodies were measured by Western blot (C) serum from a patient with melanoma was used to probe lysates (15μg of protein/lane) from a melanoma cell line (FEMX) or a human embryonic kidney cell line (HEK 293) at different times after anti-OX40.
