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Expression of Pdgfra and Sox10 in Pdgfra conditional mutants. (A-H′) Spinal cord sections from control (Olig1+/cre;Pdgfra+/+) and double mutant (Olig1+/cre;Pdgfrafl/fl) mice at various embryonic stages were subjected to in situ hybridization with Pdgfra (A-D′) or Sox10 (E-H′) riboprobes. Pdgfra was completely abolished, whereas Sox10 expression was reduced and restricted to the ventral half.
