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. Author manuscript; available in PMC: 2014 Jan 22.
Published in final edited form as: Exp Gerontol. 2012 Oct 5;48(2):240–249. doi: 10.1016/j.exger.2012.09.006

Fig. 2.

Fig. 2

Feeding of NaBu during the larval + adult stages has dose-dependent effects on longevity of Ra and La adults. Feeding NaBu at either dose throughout the developmental and adult stages has different effects on the Ra (Panel A) or La (Panel B) strains relative to controls. In the Ra strains, the low dose results in a significant extension of median, but not maximum, age relative to controls (log-rank test, X2=26.81, 1 df, p<0.0001) while the high dose results in a significant decrease of median but not maximum, age (X2=20.21, 1 df, p<0.0001). In the La strains, the low dose has no effect (p=0.9415) while the high dose significantly decreases the median but not maximum age (X2=13.04, 1 df, p=0.0003). The median life spans of the several cohorts are listed in the legends of Panels A and B. The N for each Panel A cohort is: control=169; low dose=136; and high dose=132. The N for each Panel B cohort is: control=160; low dose=135; and high dose=135.