Table 1.
Univariate analysis showed that patients with high level of S4F had <5-fold increase of risk for biochemical recurrence compared with those with low level of S4F [HR=5.426 (hazard ratio, 5.426 (95% confidence interval, 2.19–13.40); P = 0.0002]. S4F was an independent indicator for biochemical recurrence. [hazard ratio, 7.551 (95% confidence interval, 2.345–24.312); P = 0.000].
| Univariate | HR | 95.0% CI for HR | p-value | |
|---|---|---|---|---|
| Lower | Upper | |||
| S4F Epi Cyto (groups) | 5.43 | 2.20 | 13.40 | .0002 |
| Multivariate | HR | 95.0% CI for HR
|
p-value | |
|---|---|---|---|---|
| Lower | Upper | |||
|
| ||||
| Ln (PSA) | 2.03 | 1.14 | 3.60 | .0160 |
| LN | 21.59 | 6.84 | 68.17 | <0.0001 |
| ECE | 1.67 | .53 | 5.25 | .3811 |
| SVI | 1.25 | .47 | 3.38 | .6534 |
| MARGINS | 5.22 | 1.91 | 14.29 | .0013 |
| Gleason Grade | 4.70 | 1.88 | 11.72 | .0009 |
| S4F Epi Cyto (groups) | 7.55 | 2.35 | 24.31 | .0007 |