Skip to main content
. 2013 Aug 15;134(1):133–140. doi: 10.1038/jid.2013.293

Figure 5.

Figure 5

Melanoma regression is associated with melanophage and apoptotic activity. (a) Hematoxylin and eosin (H&E) staining of a regressing BRAFV600Emitf melanoma showing almost total regression with prominent melanophages (scale bar=200 μm). Boxed region is enlarged in right panel (scale bar=100 μm). (b) A regressing tumor, showing subtotal regression with melanoma cells present (scale bar=100 μm). Boxed region is enlarged in right panel (scale bar=50 μm). (c) Images of nonregressing (<26 °C) and regressing (32 °C) BRAFV600Emitf melanomas (as shown in b), stained with an antibody to detect cleaved-Caspase-3 (scale bar=50 μm).