Figure 3. Differences in age, survival, and repeat length.
Associations of repeat length with age at onset (n=20, A) and age at collection (n=21, B) in FTD patients are shown. A regression line is displayed for each plot of correlation to enhance visual display. Survival following disease onset according to 25th percentile repeat length (11·1 kb [~1467 repeat units]) in the cerebellum of the overall cohort is demonstrated (n=10≤25th percentile, n=28>25th percentile, C). In addition, survival following disease onset according to 25th percentile repeat length (11.1 kb) in the cerebellum of FTD patients is shown (n=5≤25th percentile, n=14>25th percentile, D). Repeat lengths in the frontal cortex (n=21 FTD, 11 FTD/MND, 9 MND, E), cerebellum (n=20 FTD, 12 FTD/MND, 8 MND, F), and blood (n=15 FTD, 9 FTD/MND, and 23 MND, G) are not significantly different between disease subgroups; the sample median is represented by a solid horizontal line.
