Table 1.
Studies which have investigated the effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson's disease on tasks involving inhibition of prepotent responses, response selection under conflict or decision-making under conflict.
| Investigators | Medication status | Worse with STN DBS | Unchanged with STN DBS | Improved with STN DBS | |
|---|---|---|---|---|---|
| 2000 | Jahanshahi | Off | Stroop interference task | ||
| 2002 | Schroeder | Off | Stroop interference task | ||
| 2004 | Hershey | Off | Go no Go RT with high target frequency | Go no Go RTs with lower target frequency | |
| 2006 | van den Wildenberg | On | Go no Go RTs | Stop signal RT task | |
| 2006 | Witt | On | Stroop interference task | ||
| 2007 | Thobois | Off | Fast-paced RNG | ||
| 2007 | Frank | On | Probabilistic decision making under high conflict | ||
| 2009 | Ballanger | Off | Go no go RT | ||
| 2009 | Ray | On | Stop signal RT task | ||
| 2010 | Wylie | On | Simon Task—fast responses | Simon task—slow responses | |
| 2010 | Hershey | Off | Go no Go RT—with ventral STN DBS | ||
| 2010 | Greenhouse | On | Stop signal RT task—DBS of ventral vs. dorsal contacts | ||
| 2010 | Yugeta | On | Anti-saccade task | Memory guided saccades | |
| 2011 | Swann | On | Stop signal RT task | ||
| 2012 | Mirabella | Off | Stop signal RT task | ||
| 2011 | Cavanagh | Probabilisitic decision making under high conflict | |||
| 2012 | Coulthard | On and Off | Probabilistic decision making requiring integration of conflictual information | ||
| 2013 | Favre | On | Release of proactive inhibition in unwarned simple RT | ||
| 2013 | Obeso | On | Conditional stop signal RT task | ||
| 2013 | Green | On | Moving dots task | ||
| in preparation | Pote | On | Moving dots task | ||