Table 3.
Consistent patients and consistent controls: between-group fMRI results for trial difficulty1
| Brain regions | Cluster | Voxels | x | y | z | t | P |
|---|---|---|---|---|---|---|---|
| Frontal cortex – R | 6010 | 22 | −2 | 54 | 5.06 | <0.001 | |
| Superior frontal gyrus | 297 | ||||||
| Middle frontal gyrus | 259 | ||||||
| Precentral gyrus | 275 | ||||||
| Frontal cortex – L | |||||||
| Superior frontal gyrus | 417 | ||||||
| Middle frontal gyrus | 382 | ||||||
| Medial wall/Dorsal ACC | |||||||
| Superior medial frontal gyrus – R | 220 | ||||||
| Superior medial frontal gyrus – L | 319 | ||||||
| Supplementary motor area – R | 679 | ||||||
| Anterior cingulate gyrus – R | 213 | ||||||
| Anterior cingulate gyrus – L | 60 | ||||||
| Middle cingulate gyrus – R | 35 | ||||||
| Middle cingulate gyrus – L | 294 | ||||||
| Parietal cortex – L | |||||||
| Inferior parietal lobule | 326 | ||||||
| Postcentral gyrus | 175 | ||||||
Other conventions as in Table 2.
1
Differential activation between the healthy controls (n = 14) and patients with schizophrenia (n = 14). For controls>patients, contrast is hard>easy trials; for patients>controls, contrast is easy>hard trials.