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Effects of DGAT1 deficiency on energy metabolism in mice. A: Male mice (10 weeks old) fed a high-fat diet for 2 weeks. Note the leaner appearance of the Dgat1−/− mouse. Image courtesy of C. Villanueva. B: Energy expenditure and food intake in wild-type and Dgat1−/− mice. C: Weight curves for inbred wild-type, Dgat1+/−, and Dgat1−/− mice fed a high-fat diet (unpublished observations).
