Fig. 6. Effects of VPA on lysine acetylation of α-synuclein in rat primary astrocytes. Viral particles encoding wild type α-synuclein were infected for 24 hr and cells were treated with VPA and SP600125 (2 μM). After 24 hr, cultured cells were harvested for Western blot analysis. Immunoblots of lysates from treated rat primary astrocytes were immunoprecipitated with acetyl lysine or flag antibody as described. Immunoblots were probed with acetyl lysine or flag antibody. The data are representative of two independent experiments.
