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Adverse events.
| Adverse event | Grade 1 |
Grade 2 |
Grade 3 |
Grade 4 |
TOTAL |
|---|---|---|---|---|---|
| Ataxia | 4 | 4 | 0 | 0 | 8 |
| Constipation | 10 | 6 | 6 | 0 | 22 |
| Depression | 5 | 1 | 0 | 0 | 6 |
| DVT | 1 | 0 | 3 | 0 | 4 |
| Fatigue | 11 | 3 | 1 | 0 | 15 |
| Muscles weakness | 5 | 3 | 1 | 0 | 9 |
| Neuropathy | 9 | 1 | 0 | 0 | 10 |
| Pulmonary embolism |
0 | 0 | 0 | 1 | 1 |
| Rash | 6 | 4 | 1 | 0 | 11 |
| Sinus bradycardia | 9 | 0 | 0 | 0 | 9 |
| Sinus tachycardia | 2 | 0 | 0 | 0 | 2 |
| WBC (low) | 2 | 0 | 0 | 0 | 2 |
| Total adverse events |
64 | 22 | 12 | 1 | 99 |
