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(A) Exponential growth of the mean lifetime before extinction indicates that CRISPR stabilizes the stochastic virus-host system when hosts have the upper hand. (B) The constant a transect shows that stabilization is most effective in the intermediate viral mutation regime when viruses and hosts coexist. (C) A transect of Fig. 1B for a constant μ also shows that virus/host coexistence and LV stabilization are most pronounced in the intermediate range of spacer acquisition rates (a).
