Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Binding affinities of transition metals to α- and β-PrP91-231 and PrP52-98
| Metal (measurement) | α-PrP91-231 | β-PrP91-231 | PrP52-98 |
|---|---|---|---|
| Cu2+ (direct) | 41 fM | 33 fM | 8 fM |
| Ni2+ (direct) | 16 nM | 0.8 nM | 14 nM |
| Ni2+ (competition) | 17 nM | 1.1 nM | 16 nM |
| Zn2+ (competition) | 98 nM | >5 mM | 410 nM |
| Mn2+ (competition) | 202 μM | >5 mM | 2.95 mM |
