Table 4.
Psychiatric and Substance Abuse History Among Hispanics (N=85)
| 5-HTTLPR Genotype | ||||
|---|---|---|---|---|
| L’L’ (n=21) |
L’S’ (n=35) |
S’S’ (n=29) |
p-value | |
| Lifetime Anxiety Disorder (%) | 12.5 | 12.9 | 8.3 | 0.85 |
| Lifetime Major Depression (%) | 25.0 | 16.1 | 12.5 | 0.58 |
| Baseline Depressive Symptoms | ||||
| Mean (SD) BDI score | 8.48 (7.7) | 8.14 (7.1) | 8.46 (7.5) | 0.98 |
| Baseline Severity of Depression (%) | 0.46 | |||
| None (BDI<=10) | 66.7 | 71.4 | 67.9 | |
| Minimal (BDI=11–14) | 19.0 | 8.6 | 7.1 | |
| Mild (BDI=15–19) | 9.5 | 8.6 | 14.3 | |
| Moderate (BDI=20–29) | 0.0 | 11.4 | 10.7 | |
| Severe (BDI>=30) | 4.8 | 0.0 | 0.0 | |
| Lifetime Alcohol Use Disorder (%) | 62.5 | 48.4 | 54.2 | 0.65 |
| Lifetime Drug Use Disorder (%) | 50.0 | 38.7 | 37.5 | 0.70 |
| Medications at Baseline (% of patients) | ||||
| Anxiolytics | 14.3 | 5.7 | 0.0 | 0.11 |
| SSRIs Antidepressants | 9.5 | 17.1 | 20.7 | 0.57 |
| Non-SSRIs Antidepressants | 14.3 | 17.1 | 17.2 | 0.95 |