Figure 3.
Pathological findings for case 2. In the angular gyrus, (A) frequent amyloid-beta positive neuritic plaques (3F4 antibody, hematoxylin counterstain) and (B) sparse to moderate neurofibrillary tangles and neuropil threads are seen (PHF-1 antibody, hematoxylin counterstain). (C) Dorsolateral frontal cortex shows frequent TDP-43-immunoreactive crescentic or compact neuronal cytoplasmic inclusions with surrounding wispy neuropil threads, consistent with FTLD-TDP, Type A. Scale bars indicated 500 μM (A), 100 μM (B), and 50 μM (C).