Figure 3. Changes in gene and isoform expression are distinct in both fetal and hypertrophic hearts.
A, Each isoform expressed in the fetal or sham group above 3 FPKM is plotted as a gray dot, where the x-coordinate is the gene expression fold change relative to sham and the y-coordinate is the isoform fold change (relative to sham). Blue dots represent a transcript where both the isoform and gene expression are significantly different from sham (absolute fold change >1.5 and an adjusted p-value < 0.05). Red dots represent transcripts where only isoform expression is significantly altered. B, TAC gene and isoform expression plotted in a similar fashion as A.