TABLE 1.
POPULATION CHARACTERISTICS AND BACTERIAL ORGANISMS
| Characteristics | Patients with PNTM (n = 58) | PCD (n = 8) | CF (n = 5) | Healthy Control Subjects (n = 41) |
|---|---|---|---|---|
| Mean ± SD age, yr |
63 ± 9 |
36 ± 18 |
46 ± 14 |
40 ± 15 |
| Female gender |
51 (88)* |
7 (88) |
2 (40) |
36 (88) |
| Ethnicity |
|
|
|
|
| White |
54 (93) |
5 (62) |
5 (100) |
26 (63) |
| Asian |
4 (7) |
1 (13) |
0 (0) |
3 (7) |
| Never smokers |
33 (57) |
8 (100) |
5 (100) |
nd |
| CFTR carriers |
14 (24) |
3 (38) |
5 (100) |
nd |
| Scoliosis |
30 (52) |
nd |
nd |
nd |
| Joint hypermobility |
12 (21) |
nd |
nd |
nd |
| Positive thumb–wrist sign |
12 (21) |
nd |
nd |
nd |
| Mitral valve prolapse |
4 (7) |
0 (0) |
nd |
nd |
| Cough |
55 (95) |
8 (100) |
5 (100) |
nd |
| Bronchiectasis |
58 (100) |
8 (100) |
5 (100) |
nd |
| NTM positive sputum at collection |
31 (53) |
5 (63) |
3 (60) |
nd |
| On NTM therapy at collection |
31 (53) |
6 (75) |
5 (100) |
nd |
| Elevated inflammatory markers at collection |
39 (67) |
6 (75) |
2 (40) |
nd |
| Macrolide exposure at collection |
24 (47) |
4 (50) |
5 (100) |
nd |
| Immunomodulatory drugs |
4 (7) |
0 (0) |
2 (40) |
nd |
| BMI ± SD |
21.7 ± 4.7 |
22.3 ± 8.3 |
26.3 ± 6.5 |
nd |
| Mycobacteria |
|
|
|
|
| MAC |
41 (71) |
3 (60) |
1 (33) |
|
| MAB |
6 (10) |
2 (40) |
2 (67) |
|
| MAC and MAB |
10 (17) |
|
|
|
| Mycobacterium xenopi | 1 (2) |
Definition of abbreviations: BMI = body mass index; CF = cystic fibrosis; CFTR = cystic fibrosis transmembrane conductance regulator; MAC = clinical strain of Mycobacterium avium; MAB = clinical strain of Mycobacterium abscessus; nd = not detected; NTM = nontuberculous mycobacteria; PCD = primary ciliary dyskinesia; PNTM = pulmonary nontuberculous mycobacteria.
*
Values are n (%) unless otherwise noted.