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. Author manuscript; available in PMC: 2013 Aug 5.
Published in final edited form as: J Immunol. 2010 Mar 1;184(7):4006–4016. doi: 10.4049/jimmunol.0903009

FIGURE 3.

FIGURE 3

B cell depletion reduces spleen CD4+ T cell numbers. Changes in (A) spleen or (B) peripheral lymph node CD4+ and CD8+ T cell numbers following B cell depletion. Circles represent individual mice that were given control (open) or CD20 (closed) mAb, with spleen and peripheral lymph node (pooled axial, inguinal, and brachial nodes) lymphocytes harvested 21 (experiment 1) or 28 (experiments 2–3) d later. Bar graphs indicate means (± SEM) of pooled CD4+ and CD8+ T cell numbers from all three experiments. Significant differences between means are indicated: *, p<0.05.