Skip to main content
. 2013 Aug 7;19(29):4718–4725. doi: 10.3748/wjg.v19.i29.4718

Table 1.

Study characteristics

Ref. Study design Active: control (n:n) Transit timeoutcome, method Probiotic strain Daily dosage(109 cfu) Delivery method Treatmentduration (d)
Agrawal et al[14] Parallel groups 17:17 CTT, radiopaque markers B. lactis DN-173 010 25.0 Active: Yogurt + probioticControl: Nonfermented milk-based product 28
Bartram et al[15] Cross-over 12 OATT, radiopaque markers B. longum   > 0.5 Active: Yogurt with 2.5 g lactulose + probioticControl: Yogurt 21
Bouvier et al[16] Parallel groups 36:36 CTT, radiopaque markers B. lactis DN-173 010 97.5 Active: Probiotic fermented milkControl: Heat-treated probiotic fermented milk 11
Holma et al[17] Parallel groups 12:10 TITT, radiopaque markers L. rhamnosus GG 20 Active: Buttermilk + probiotic and white wheat breadControl: White wheat bread 21
Hongisto et al[18] Parallel groups 16:14 TITT, radiopaque markers L. rhamnosus GG 15 Active: Yogurt + probiotic and low fiber toastControl: Low fiber toast 21
Malpeli et al[19] Cross-over 83 OCTT, carmine red dye B. lactis BB12L. casei CRL 431 2-20 2-12 Active: Yogurt with 0.625 g inulin and oligofructose + probioticControl: Yogurt 15
Marteau et al[20] Cross-over 32 CTT, radiopaque markers B. lactis DN-173 010 18.75 Active: Yogurt + probioticControl: Yogurt 10
Rosenfeldt et al[21] Cross-over 13 GTT, radiopaque markers L. rhamnosus 19070-2,L. reuteri DSM 12246 20 20 Active: Freeze-dried powder + probioticControl: Skimmed milk powder w/dextrose 18
Rosenfeldt et al[21] Cross-over 13 GTT, radiopaque markers L. casei subsp. alactus CHCC 3137,L. delbrueckii subsp. lactis CHCC 2329,L. rhamnosus GG 20 20 20 Active: Freeze-dried powder + probioticControl: Skimmed milk powder w/dextrose 18
Sairanen et al[22] Parallel groups 22:20 CTT, radiopaque markers B. longum BB536, B. lactis 420,L. acidophilus 145 2.4-181 0.48 Active: Probiotic fermented milkControl: Fermented milk 21
Waller et al[23] Parallel groups 33:34 WGTT; radiopaque markers B. lactis HN019 1.8 Active: Capsule, maltodextrin, probioticControl: Capsule, maltodextrin 14
Waller et al[23] Parallel groups 33:34 WGTT; radiopaque markers B. lactis HN019 17.2 Active: Capsule, maltodextrin, probioticControl: Capsule, maltodextrin 14
Krammer et al[24] Parallel groups 12:12 CTT, radiopaque markers L. casei Shirota 6.5 Active: Probiotic fermented milk drinkControl: Nonfermented milk drink 28
1

Represents the reported range of total Bifidobacterium spp. cfu: Colony-forming units; CTT: Colonic transit time; GTT: Gastrointestinal transit time; OATT: Oro-anal transit time; OCTT: Oro-cecal transit time; TITT: Total intestinal transit time; WGTT: Whole gut transit time. L. rhamnosus: Lactobacillus rhamnosus; B. lactis: Bifidobacterium lactis; L. casei: Lactobacillus casei.