Figure 3. Power-law relationship betweenQrand particle mass (MW) allows direct mass determination.

a, Qr calculated from previously reported experimental SAXS data for protein only samples (Supplementary Table 1). Gel-filtration purified samples (orange) were plotted with experimental data taken from BioIsis.net (open circles). c, Qr calculated from experimental SAXS data for RNA only samples (blue) (Supplementary Table 2). Final equations in a and b can be used for mass determination of protein or RNA only samples. Due to a lack of available SAXS data for protein-nucleic acid complexes, parameters for k and c remain undetermined.