Table 1.
Semi-quantitative analysis of immune-labeling intensity of EcSOD in human breast tissues
| Tissue | N | − | + | + + | P-value vs normal breast |
|---|---|---|---|---|---|
| Normal breast | 9 | 0 | 2 | 7 | |
| DCIS | 10 | 2 | 8 | 0 | 0.001 |
| Low-grade invasive breast cancer | 7 | 6 | 1 | 0 | 0.0003 |
| High-grade invasive breast cancer | 6 | 5 | 0 | 1 | 0.003 |
Abbreviation: DCIS, ductal carcinoma in situ. Immunohistochemical staining of EcSOD was semi-quantitatively graded as negative (−), weak (+) or strong (+ +) staining in at least 50% of cells examined. P-values were calculated by the exact contingency test (3 × 2 contingency table) based on Fisher’s exact test. N represents the number of tissues examined.