Figure 2.
Dendritic cell (DC) CD11c+ surface expression and phagocytosis are suppressed by n-3 long-chain polyunsaturated fatty acids (LCPUFAs). (a)The surface expression of CD11c on DCs isolated from C57BL/6 mice consuming a control or n-3 LCPUFA diet. (b) Sample flow cytometry histograms of fluorescence uptake of Escherichia coli bioparticles. (c) The amount of E. coli bioparticles taken up as indicated by the mean fluorescence intensity (MFI), which was was normalized due to a slight variation in the number of bioparticles administered to the cells between experiments. Data are from six to eight independent experiments in (a) and four for (b) and (c). Asterisk indicates significance from control: *P < 0·05.