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. Author manuscript; available in PMC: 2014 Sep 26.
Published in final edited form as: Neuroscience. 2013 Jan 20;249:53–62. doi: 10.1016/j.neuroscience.2013.01.023

Fig. 1. Frontoamygdala circuit of Fear.

Fig. 1

A simplified cartoon of the brain circuitry involved in emotion reactivity and regulation related to threat processing. The amygdala receives multimodal sensory signals that may initiate a fear response, while top-down input from the infralimbic prefrontal cortex to the amygdala can dampen or extinguish fear responses generated there. Abbreviations: BA, basal amygdala; CE, central amygdala; IL, infralimbic prefrontal cortex; ITC, intercalated; LA, lateral amygdala; PL, prefrontal cortex; vmPFC, ventromedial prefrontal cortex. Adapted from Casey et al 2013.