Fig 2. Brain regions exhibiting significant differences in functional connectivity of DMN.
(a) Brain regions showed significant differences in functional connectivity of DMN between healthy subjects, patients with aMCI and patients with AD (Pα<0.05 (uncorrected P <0.01, F>4.78, 1000mm3, AlphaSim corrected)). The following were results of the post hoc two-sample t tests between pairs of the healthy subjects, patient with AD and aMCI groups in voxel-wise analysis. The significant differences in brain regions was found (b) in patients with aMCI compared with healthy subjects, (c) in patients with AD compared with patients with aMCI (d) and in patients with AD compared with healthy subjects (Pα<0.05). The images are oriented with the anterior side placed at the top and the left side placed to the right.