Figure 1.
The bioenergetic profiles of human leukocytes and platelets. The bioenergetic profiles of monocytes (a), lymphocytes (b), platelets (c), and neutrophils (d) were determined using the extracellular flux analyzer. The basal measurements of oxygen consumption rates (OCR) were followed by sequential injections of 0.5 μg/ml oligomycin (0.75 μg/ml for platelets), 0.6 μM FCCP, and 10 μM antimycin A to determine the indices of mitochondrial function. Data expressed as mean±s.e.m. from representative donor profiles, n=3–5 assay replicates per sample.