Figure 7.
Clinical evaluation of the effects of platelet-rich plasma and insulin injection on long-term human fat graft maintenance. (A): Bar graph showing the percentage of restored fat graft volume maintenance with different PRP concentrations after 3, 6, 12, 24, and 52 weeks. (B): Bar graph showing the percentage of restored fat graft maintenance in patients treated with fat graft + 40% vol/vol PRP and the local injection of 0.5 ml human recombinant insulin (40 μM) performed 7 and 15 days after grafting in comparison with patients receiving fat graft + 40% PRP vol/vol alone. (C): Bar graphs showing the different percentages of patients presenting symptoms and sign default at different times after the treatment with fat graft + 40% vol/vol PRP alone or plus insulin injection. Data are mean ± SE. (D): Pre- and postoperative photos of a patient treated with fat graft + 40% PRP + insulin. (E): Pre- and postoperative spectral selection attenuated inversion recovery-magnetic resonance imaging and T2-MRI of the same patient. *, ** indicate p < .05 and p < .01, respectively. Abbreviations: CTR, control; PRP, platelet-rich plasma; preop, preoperative; postop, postoperative; SPAIR-MRI, spectral selection attenuated inversion recovery-magnetic resonance imaging; T2-MRI, T2-weighted-magnetic resonance imaging.