Table V.
2DS1pos C1:C1 NK clones co-expressing inhibitory KIR for self-HLA-class I
| Donor HLA-C genotype | KIR phenotype | Target HLA-C genotype | n | Cytolytic
|
p | |
|---|---|---|---|---|---|---|
| Yes, n (%) | No, n (%) | |||||
| C1:C1 | 2DS1 and 2DL2/3 | C2:C2;Bw4 | 46 | 42 (91) | 4 (9) | <0.0001a |
| C1:C2;Bw4 | 1 (5) | 18 (95) | ||||
| C1:C1 | 2DS1 and 3DL1 | C2:C2;Bw4 | 2 | 0 (0) | 2 (100) | |
Frequency of cytolytic clones to targets with different HLA-C genotype is compared.