Figure 7. Prolonged BBB leakage in MMP-9-null mice.
Representative images of implants from WT (A, C, E), MMP-9 -null (B, D, F) mice stained with anti-MSA Ab and visualized with the peroxidase reaction (brown color) are shown. (G) Extravasated mouse serum albumin (MSA) was evaluated by morphometric analysis of stained sections using Metamorph and suggested complete repair in WT mice. In contrast, repair of the BBB in MMP-9-null was compromised. * p value <0.05. Scale bar = 50μm (A-F).
